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During TPRT, the R2-encoded endonuclease recognizes the conserved retrotransposon upstream motif and introduces a site-specific nick at the retrotransposon-associated insertion site within the 28S rDNA 39,56,57
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And, Im am Truly grateful that I had his silent mentorship as he wasnt one to say much about pipe smoking except that one Christmas he handed me a pkg which contained two pouches of Prince Albert and a Grabow and said ,boy if youre gonna smoke ya ought to smoke this